So, when a new person signs up to your site (via your newly created signup box), they will (after confirming their subscription) start to receive the set of emails that you have setup.  You can create as many as you want and schedule them to be sent out at different intervals (i.e. 1 a day, 1 a week, 1 a day and then another one in a month’s time, etc.).
Promote up-sells/cross-sells. You can even set up an autoresponder sequence for someone after they purchase and get repeat customers. Depending on the products you sell, you could offer an upsell, or cross-sell related products. For example, if someone buys a digital camera, you can offer to add a lens, a tripod, and other accessories to their order before it ships. Or, if you sell products that people buy frequently (like food or disposable items, like diapers), you can automatically send them offers for new items when you know they’re about due for another order.

A lead magnet (a.k.a. an optin bribe) is something amazing that you give away for free in exchange for an email address. This doesn’t have to cost you anything to create; most lead magnets are digital materials like PDFs, MP3 audio files, or videos that you can create yourself at minimal or no cost. It can be absolutely anything you want, so long as it provides value to your visitors for free.
We’ve changed email marketing from iContact to MailChimp and, just now, Aweber. We changed from iContact to MailChimp to cut costs. We then switched to Aweber because Mailchimp will not allow you to start an Autoresponder series on an imported list PLUS, as you mentioned, Aweber has much more robust measuring/management tools. However, people should be aware that Aweber requires imported subscribers to opt-in all over again.

You need to add few details like, Name of your list, Sender name for the list, reply-to email, default subject and few more details. Most of the fields are self-explanatory, so you will not find yourself lost at any moment. There are few fields which are mandatory, for example, Address of your company (In the case of bloggers, you can add your home address). You can leave the default subject field empty, as this will be used when you are sending your first email campaign.
“As my list has grown, I’ve just remained focused on the next metric right ahead of me. First it was just to hit 200 subscribers, then 300 subscribers, then 400 subscribes. Eventually the goal was 1,000 subscribers, then 2,000 etc. etc.  As I’ve gone past 10,000 and 20,000 and beyond I’ve actually started to focus more not on the sheer number but on engagement.” – John Corcoran, Smart Business Revolution
A low open rate means that people have started to either ignore your messages, or delete them as soon as they receive them. (Or, what I do, is mark them as “read” and just leave them there – probably never to be actually read!) If your open rates are low, you need to work on your email marketing game. Take a look at the previous emails you’ve sent them, or at your subject lines. Something about those emails has deterred your subscriber from opening them up, so tweak and test until you get higher open rates.

I have been using PLR products for some time now as an internet marketer to build my list and to sell. Some products are not easy to sell. And I now have a Ebook Store too that I am stocking with the latest products thanks to your course. This is the best training I have seen in quite some time. And they have over delivered! Better get yours now if you are serious about starting an online business. - Vince Atkinson
With Aweber however, this is not that easy to do. With Aweber, each and every one of your subscribers is tagged with a message number which indicates which followup emails they have received already. To prevent a subscriber from receiving a specific followup email, you must set the subscriber’s message number to be higher than the email sequence number.
I’ve been using Aweber for about 2 years on 2 blogs now and I’m really happy with it. One uses a follow-up broadcast (i.e. every 2 weeks a new “how-to” is sent) and has just over 1,000 subscribers (from about 50 when I started a couple of years ago) while the other blog uses a blog broadcast (it sends out an email with the week’s news) and has about 250 subscribers.
Like a lot of bloggers I give away a free eBook as a way of capturing email subscribers. This is a very clumsy process using Feedburner as you cannot set up an automatic response to send the eBook as soon as someone subscribers. Rather, you have to add a download link to your feed and then hope the new subscriber understands that they don’t get an email until you write a new post.

Advanced: When people subscribe to my list, I can create a main course and then invite people to self-select into the various interest areas that are relevant to them. For example, if you are tired of spinning your wheels and don’t know what to do next in your business, and you click a link related to that, you’d then get tagged as “Nurture: focus and planning” and that would then automatically unsubscribe you from the main course, and put you into a new course designed to provide you with value that could help you figure out your next steps and get focused.
Tagging subscribers allows you to segment your email list based on certain actions your subscribers take, such as signing up from a specific form, downloading or purchasing a certain product, clicking a specific link, etc. Then, you can send emails or run campaigns for specific tags, and on top of all that there are a ton of automation and sequencing logic you can set up to trigger certain events.   
Before you can send AWesome emails with AWeber, you'll need someone to send it to. The easiest way to begin building your list is to import contacts that have opted-in to your email list, or gave you permission to send them emails. These could be subscribers you've emailed from another provider, or a list of contacts that you've built through your business.
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